Released on = June 21, 2007, 1:57 pm

Press Release Author = GTCbio

Industry = Pharmaceuticals

Press Release Summary = Dr. Aaron B. Kantor, Executive Director of Cell and
Molecular Biology, Biomarker Discovery Sciences at PPD, Inc. will present on
Pharmacodynamic Biomarkers Identified with Broad-Based Phenotyping at GTCbio's
Rediscovering Biomarkers: Detection, Development & Validation Conference taking
place on July 23-24, 2007 at the San Diego Marriott La Jolla in La Jolla, CA.

Press Release Body = Dr. Aaron B. Kantor, Executive Director of Cell and Molecular
Biology, Biomarker Discovery Sciences at PPD, Inc. will present on Pharmacodynamic
Biomarkers Identified with Broad-Based Phenotyping at GTCbio's Rediscovering
Biomarkers: Detection, Development & Validation Conference taking place on July
23-24, 2007 at the San Diego Marriott La Jolla in La Jolla, CA.

Broad-based phenotyping provides fundamental information about disease and treatment
and enables discovery of new and useful biomarkers. We applied SurroScanTM laser
scanning cytometry, immunoassays for specific soluble proteins, and
mass-spectrometry based differential proteomics which track thousands of analytical
variables, to the identification of pharmacodynamic markers for interferon-1-beta in
multiple sclerosis subjects. A strong pharmacodynamic effect was observed 1.5 vs. 6
days post weekly drug injection. Significant differences included interferon-
inducible gene products, and monocyte-associated variables. Multiple differences
were also observed among multiple sclerosis and healthy control cohorts.

GTCbio's Rediscovering Biomarkers: Detection, Development & Validation Conference
provides comprehensive coverage of a wide range of topics including Biomarker
Application in Oncology Clinical Development, Drug Discovery, Development and
Diagnostics of Biomarkers, Tools for Improving Measurement, Safety and Validation of
Biomarkers, and Upcoming Technology and Trends.

For more information including a detailed agenda, exhibitor opportunities and
registration information visit
http://www.gtcbio.com/conference/conferenceDetails.aspx?id

Web Site = http://www.gtcbio.com

Contact Details = ABOUT GTCbio

GTCbio organizes conferences specifically for the biomedical and biopharmaceutical
industries. Our goal is to facilitate the exchange of biopharmaceutical and
biomedical intelligence between industry leaders, academic and government
organizations, and the financial community.

GTCbio is a subsidiary of Global Technology Community, LLC, a privately held company
founded in 2002.

Contact: GTCBIO (626) 256-6405, (626) 256-6460 fax, raniah@gtcbio.com